site stats

Ctgf growth factor

WebConnective tissue growth factor, also known as CCN2, is a cysteine-rich matricellular protein involved in the control of biological processes, such as cell proliferation, … WebBy this attempt, we identified connective tissue growth factor (CTGF) as a novel factor highly expressed in infected hearts. Further investigations by quantitative reverse …

CTGF expression. CTGF, connective tissue growth factor; CTX, …

WebMar 10, 2024 · Connective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN protein family of secreted proteins with roles in diverse biological processes. … WebHuman connective tissue growth factor (CTGF), also known as CCN2, and Insulin-like growth factor-binding protein 8, is a matricellular protein encoded by the gene CTGF. Along with CYR61 (CCN1) and NOV (CCN3), CTGF belongs to the CCN family of extracellular matrix-associated heparin binding proteins. The CCN proteins contain IGFBP, Von ... greenfish jobs https://dynamikglazingsystems.com

CTGF enhances resistance to 5-FU-mediating cell apoptosis …

WebNov 1, 2016 · Introduction. Connective tissue growth factor (CTGF/CCN2) is a secreted matricellular protein known to play important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, vascular differentiation, and myofibroblast formation, all of which can lead to tissue remodeling and changes in organ … CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, … See more Members of the CCN protein family, including CTGF, are structurally characterized by having four conserved, cysteine-rich domains. These domains are, from N- to C-termini, the insulin-like growth factor … See more Knockout mice with the Ctgf gene disrupted die at birth due to respiratory stress as a result of severe chondrodysplasia. Ctgf-null mice also show defects in angiogenesis, with impaired interaction between endothelial cells and pericytes … See more • Ctgf/hcs24 CAESAR • CYR61 (CCN1) See more CTGF is associated with wound healing and virtually all fibrotic pathology. It is thought that CTGF can cooperate with TGF-β to induce sustained fibrosis and to exacerbate extracellular matrix production in association other fibrosis-inducing conditions. … See more • Human CTGF genome location and CTGF gene details page in the UCSC Genome Browser. See more WebNov 19, 2012 · Proteomic profiling revealed that connective tissue growth factor (CTGF; CCN2) was overrepresented in the conditioned media of sFRP2-overexpressing MSCs and MSC-derived CTGF could thus be an ... flushed ceiling lighting

Connective Tissue Growth Factor Overexpression in …

Category:Multifunctional regulatory protein connective tissue growth factor ...

Tags:Ctgf growth factor

Ctgf growth factor

CTGF related genes - GeneCards Search Results

WebMay 31, 2024 · Connective tissue growth factor (CTGF) plays important roles in the development and regeneration of the connective tissue, yet its function in the nervous system is still not clear. CTGF is expressed in some distinct regions of the brain, including the dorsal endopiriform nucleus (DEPN) which has been recognized as an epileptogenic …

Ctgf growth factor

Did you know?

WebOct 4, 2012 · Background The pro-fibrogenic cytokine connective tissue growth factor (CTGF) plays an important role in the development and progression of fibrosis in many organ systems, including liver. However, its role in the pathogenesis of hepatitis C virus (HCV)-induced liver fibrosis remains unclear. Methods In the present study, we assessed … WebSelect search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources

WebConnective Tissue Growth Factor or CTGF is a protein of the extracellular matrix variety. Also known as CCN2, this matricellular protein is part of the CNN group. Connective … WebJun 6, 2012 · Key roles for connective tissue growth factor (CTGF/CCN2) are demonstrated in the wound repair process where it promotes myofibroblast differentiation and angiogenesis. Similar mechanisms are active in tumor-reactive stroma where CTGF is expressed. Other potential roles include prevention of hypoxia-induced apoptosis and …

WebConnective Tissue Growth Factor (CTGF, CCN2, HCS24, IGFBP8, NOV2) is a heparin-binding glycoprotein with molecular weight of 36–38 KDa, composed of 343–349 amino acid residues and belonging to the CCN family. The CCN family of proteins is a complex family of multifunctional proteins containing six members designated CCN1 to CCN6. WebOct 26, 2024 · Connective tissue growth factor (CTGF), also known as CCN family protein 2 (CCN2), is composed of four domains, including insulin-like growth factor binding protein-like (IGFBP), von Willebrand factor type C repeat (VWC), thrombospondin type 1 repeat (TSP1), and C-terminal cystine-knot (CT) modules . It is a cysteine-rich …

WebFeb 25, 2024 · Expression of connective tissue growth factor (CTGF) is elevated in affected organs in virtually every fibrotic disorder and in the diseased human myocardium. Mice were subjected to treatment with a CTGF monoclonal antibody (mAb) during infarct repair, post-MI left ventricular (LV) remodeling, or acute ischemia−reperfusion injury. ...

WebCTGF, connective tissue growth factor; CTX, captopril group; DC, docetaxel-captopril group; DTX, docetaxel group; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; H, control group; STR, stricture ... green fishing shirtWebMay 28, 2024 · The overexpression of a matricellular protein, connective tissue growth factor (CTGF), is a hallmark of fibrosis in multiple tissues in the mediation of the pro … green fishing lights underwaterWebOct 29, 2024 · Connective tissue growth factor (CTGF) is a key signaling and regulatory molecule involved in different biological processes, such as cell proliferation, … greenfish labsWebAug 1, 2024 · CTGF (connective tissue growth factor), also known as CCN2, is one of the best-studied members of the CCN family [1], a family of regulatory proteins of the … flushed cheeks in childrenWebJul 22, 2002 · Connective-tissue growth factor (CTGF) is a secreted protein implicated in multiple cellular events including angiogenesis, skeletogenesis and wound healing 1. It is … green fish knifeWebMay 8, 2024 · Connective tissue growth factor (CTGF), a secreted protein, is thought to be involved in extracellular matrix remodeling during development and pathologic … green fishing poleWebConnective tissue growth factor (CTGF/CCN2) ELISA: a novel tool for monitoring fibrosis -Dendooven A, Gerritsen KG, Nguyen TQ, Kok RJ, … greenfish maitland